Severe but rare side effects of taking Carbimazole: Carbimazole can very rarely be associated with a condition called agranulocyrtosis (low neutrophil count) which can have symptoms including sore throat, bruising or bleeding, mouth ulcers, fever, malaise. Carbimazole is used to treat hyperthyroidism. along with all my muscles which became just like jelly! Take care, I know things will get better. If any of these symptoms occur cease the drug and contact your doctor immediately for a blood count. 13 years ago, Well, here I am, still waiting for my voice to get back to what it was! We've even employed cleaners as I just can't keep on top of that. Pyrimethamine. When I was diagnosed the weigh fell off (1.5 stone in a week!) Over the weekend my throat has been so sore and ulcerated and I have struggled to keep my eyes open. Have got another blood test on Monday. People say I look healthier and I do feel so much better. Angioedema, a serious allergic reaction with symptoms that may include swollen tongue, lips, face or throat Lung problems, with symptoms that include shortness of breath or a cough Kidney problems, with symptoms that include a reduction in the amount of urine passed, fluid retention and blood in the urine. I have no control over my body anymore, it controls me! I hate it....howong b4 u started gaining the weight back? They may also switch you to an alternative drug to do the same job. Both carbimazole and propylthiouracil can increase the risk of myelosuppression. Sore Throat Or Mouth Ulcers After Taking Carbimazole? If this is normal, the patient can continue the drug. Patient does not provide medical advice, diagnosis or treatment. If this is not possible, please see your GP or go to the emergency department. May increase the … Patient is a UK registered trade mark. Hair … You have been started on tablets to control your overactive thyroid gland. Am no longer on beta-blockers. Had a sore throat around a week and a half now. Carbimazole during pregnancy and lactation Carbimazole can be used in pregnancy. © Patient Platform Limited. My GP'so failed to notice the signs of an over active thyroid all this time (so I was informed by my own GP whom I can never get in to see). A white blood cell count should be performed if there is any clinical evidence of infection. Carbimazole: Belongs to the class of sulfur-containing imidazole derivative agents. If the patient has had both carbimazole and PTU, or you are concerned about the patient or require further information, please contact the endocrinolgy doctor on call. You have been started on tablets to control your overactive thyroid gland. If the patient attends with a fever, flu like symptoms, mouth ulcers or a sore throat, this may indicate the development of neutropaenia. If they are taking carbimazole, please prescribe propylthiouracil (PTU) in place of the carbimazole - the dose of PTU is 10 times the dose of carbimazole (for example 20mg carbimazole = 200mg PTU). Carbimazole given with a potent CYP3A4 inhibitor is predicted to increase the exposure to propiverine. I am very sad about this, I know this must sound quite trivial when we have lots of other symtoms, but, to me, it IS important for me to keep on singing! I had several sore throats and was blood tested a few times but all was ok. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T 3 and T 4 (thyroxine). I feel at least I am doing something. appropriate medical assistance immediately. Patients with low white blood cells may develop a sore throat, mouth ulcers, rash, or fever. My appetite has always been good but eating everything in site and feeling starving within 5 minutes was definately odd. I am waiting to see an endocrinologist. Carbimazole warning sheet - Patient information sheet Carbimazole information sheet for patients. Propylthiouracil. This is a very safe treatment that has been used for over 50 years. Patients should always be warned about the onset of sore throats, bruising or bleeding, mouth ulcers, fever and malaise and should be instructed to stop the drug and to seek medical advice immediately. Sore throat, fever, or mouth ulcers If you develop any of these symptoms, please stop your medication immediately and bring this letter to hospital immediately to have a blood test. If they have developed a rash, please consider switching to an alternative agent. 31 users are following. 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